Our Global Cyber Defense team is responsible for safeguarding Pfizer’s digital assets and infrastructure through proactive threat detection, response, and risk mitigation across on-premises, cloud, and hybrid environments.
The Senior Manager, Threat Remediation is responsible for owning and driving the end‑to‑end remediation of cybersecurity threats across the enterprise. This role sits at the intersection of threat detection, incident response, vulnerability management, offensive security and technology risk, ensuring that identified threats are prioritized, mitigated, and resolved in a timely, risk‑based, and compliant manner.
This role will work closely with the SOC, Cloud Services, Infrastructure, End User Computing, Engineering, GRC, Legal, Privacy, and Business stakeholders to reduce cyber risk and improve the organization’s overall security posture.
ROLE RESPONSIBILITIESOwn the threat remediation lifecycle, from intake of identified threats (incidents, alerts, vulnerabilities, control gaps) through containment, mitigation, and closure.
Translate threat intelligence, SOC findings, red team results, penetration tests, and vulnerability scans into actionable remediation plans.
Ensure remediation actions are risk‑based, prioritized, and aligned with business impact, regulatory exposure, and threat severity.
Partner with Incident Response and SOC teams during active incidents to ensure effective containment and eradication strategies.
Lead post‑incident remediation efforts, ensuring root cause analysis (RCA) is completed and systemic issues are addressed.
Track and validate completion of corrective and preventive actions (CAPAs) resulting from incidents.
Work with IT, engineering, and application owners to resolve vulnerabilities while respecting validated system change controls.
Ensure compensating controls are documented and approved where remediation is constrained due to regulatory or operational limitations.
Define and report on remediation KPIs and KRIs (e.g., mean time to remediate, overdue critical findings, repeat issues).
Provide executive‑level reporting on remediation status, risk reduction, and systemic weaknesses.
Support internal and external audits, regulatory inspections, and security assessments by demonstrating effective remediation governance.
Partner with detection, threat intelligence, and vulnerability teams to close gaps between detection and remediation.
Contribute to long‑term cyber defense strategy, including roadmap planning and technology selection.
Bachelor’s degree in Computer Science, Information Security, Engineering, or a related technical discipline, or equivalent experience.
7+ years of experience in cybersecurity, with hands-on involvement in remediation, vulnerability management, security engineering, or incident response.
Strong understanding of:
Threat actor tactics, techniques, and procedures (MITRE ATT&CK)
Incident response and containment strategies
Vulnerability management and remediation workflows
Cloud security (AWS, Azure, GCP)
Endpoint, network, identity, and application security
Familiarity with SOC tooling (SIEM, SOAR, EDR/XDR), vulnerability scanners, and ticketing/workflow systems.
Demonstrated experience in an agile work environment possessing qualities such as a collaborative mindset, adaptability to change, and a proactive problem-solving approach.
Leadership experience managing or mentoring analysts and engineers.
PREFERRED QUALIFICATIONS
Working knowledge of GxP, FDA 21 CFR Part 11, EMA, HIPAA, GDPR, and other relevant regulations.
Familiarity with security frameworks, risk management practices, and regulatory expectations relevant to pharmaceutical or life sciences organizations.
Professional certifications such as CISSP, CISM, GIAC, or equivalent credentials related to security operations or risk management.
Please apply by sending your CV and a motivational letter in English.
Work Location Assignment: Hybrid
Purpose
Breakthroughs that change patients' lives... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives.
Digital Transformation Strategy
One bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience.
Flexibility
We aim to create a trusting, flexible workplace culture which encourages employees to achieve work life harmony, attracts talent and enables everyone to be their best working self. Let’s start the conversation!
Equal Employment Opportunity
We believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms – allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees.
Disability Inclusion
Our mission is unleashing the power of all our people and we are proud to be a disability inclusive employer, ensuring equal employment opportunities for all candidates. We encourage you to put your best self forward with the knowledge and trust that we will make any reasonable adjustments to support your application and future career. Your journey with Pfizer starts here!
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.
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